SenusaBio: Software Penilaian Gen Nusantara

Chandra Prasetyo Utomo, Nashuha Insani, Puspa Setia Pratiwi, Muhamad Fathurahman, Aldo Al Deanov, Sarah Adinda Puteri, Ria Putri Rahmadani, Tyas Ikhsan Hikmawan, Ahmad Rusdan Utomo

SenusaBio is a comprehensive bioinformatics platform designed to streamline the complex process of genomic variant interpretation, pathogenicity classification, and clinical reporting. In the rapidly evolving field of precision medicine, accurately determining the clinical significance of genetic variants is critical. SenusaBio addresses this challenge by integrating advanced computational algorithms and up-to-date genomic databases to automate and standardize the variant analysis workflow. The system systematically evaluates genetic alterations against established guidelines, such as those from the American College of Medical Genetics and Genomics (ACMG), to classify variants ranging from benign to pathogenic with high confidence. Beyond classification, SenusaBio generates clear, actionable, and clinician-ready reports that translate complex genomic data into meaningful insights for patient care. By reducing manual bottlenecks and minimizing interpretation errors, this project empowers healthcare providers and geneticists to deliver faster, more accurate diagnoses, ultimately facilitating targeted therapeutic strategies and improving patient outcomes.

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